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Traditional Chinese medicine FYTF-919 (Zhongfeng Xingnao oral prescription) for the treatment of acute intracerebral haemorrhage: a multicentre, randomised, placebo-controlled, double-blind, clinical trial
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Primary sensory neuron-derived miR-let-7b underlies stress-elicited psoriasis
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COVID-19 pandemic interventions reshaped the global dispersal of seasonal influenza viruses
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The interhemispheric amygdala-accumbens circuit encodes negative valence in mice
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DNA nanomachines reveal an adaptive energy mode in confinement-induced amoeboid migration powered by polarized mitochondrial distribution
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A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell
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ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
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Pretraining a foundation model for generalizable fluorescence microscopy-based image restoration
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Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1
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Arresting the bad seed: HDAC3 regulates proliferation of different microglia after ischemic stroke
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Paternal cocaine-seeking motivation defines offspring’s vulnerability to addiction by down-regulating GABAergic GABRG3 in the ventral tegmental area.
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Two-dimensional perovskite oxide as a photoactive high-κ gate dielectric
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Plasma proteomic profiles predict future dementia in healthy adults
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Anterior cingulate cortex projections to the dorsal medial striatum underlie insomnia associated with chronic pain
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A rechargeable calcium-oxygen battery that operates at room temperature
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AAV1-hOTOF Gene Therapy for Autosomal Recessive Deafness 9: a single-arm trial
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Country-specific net-zero strategies of the pulp and paper industry
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Structural visualization of transcription initiation in action
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A novel quantitative urine LAM antigen strip for point-of-care tuberculosis diagnosis in non-HIV adults
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Different projection neurons of basolateral amygdala participate in the retrieval of morphine withdrawal memory with diverse molecular pathways
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Self-lifting Droplet Driven by the Solidification-induced Solutal Marangoni Flow
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Plasma proteomic profiles predict individual future health risk
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Asymmetric conducting route and potential redistribution determine the polarization-dependent conductivity in layered ferroelectrics
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Nanomedicine for the Detection and Treatment of Ocular Bacterial Infections
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ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries
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Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy
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Assessment of visual function in blind mice and monkeys with subretinally implanted nanowire arrays as artificial photoreceptors
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Context-dependent Regulation of Notch Signaling in Glial Development and Tumorigenesis
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Phylogenetic evidence reveals early Kra-Dai divergence and dispersal in the late Holocene
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Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury
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ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood–brain barrier integrity after traumatic brain injury
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Modulating Biological Rhythms: A Noncomputational Strategy Harnessing Nonlinearity and Decoupling Frequency and Amplitude
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Strong electric field force at the air/water interface drives fast sulfate production in the atmosphere
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Follicle-stimulating Hormone Orchestrates Glucose-stimulated Insulin Secretion of Pancreatic Islets
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Reviving Zn0 Dendrites to Electroactive Zn2+ by Mesoporous MXene with Active Edge Sites
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Herbivory limits success of vegetation restoration globally
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Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
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Neurophysiological stratification of major depressive disorder by distinct trajectories
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Modulating Biological Rhythms: A Noncomputational Strategy Harnessing Nonlinearity and Decoupling Frequency and Amplitude
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Strong electric field force at the air/water interface drives fast sulfate production in the atmosphere
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Sequencing Polymers to Enable Solid-State Lithium Batteries
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Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response
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Transcriptional and epigenetic decoding of the microglial aging process
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OPUS-DSD: deep structural disentanglement for cryo-EM single-particle analysis
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Molecular classification of hormone receptor-positive HER2-negative breast cancer
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Changing prevalence of chronic hepatitis B virus infection in China between 1973 and 2021: a systematic literature review and meta-analysis of 3740 studies and 231 million people
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The brain structure, immunometabolic and genetic mechanisms underlying the association between lifestyle and depression
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Decoding anxiety-impulsivity subtypes in preadolescent internalising disorders: findings from the Adolescent Brain Cognitive Development study
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12-inch growth of uniform MoS2 monolayer for integrated circuit manufacture
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Host traits shape virome composition and virus transmission in wild small mammals
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Optimized glycemic control of type 2 diabetes with reinforcement learning: a proof-of-concept trial
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Structure evolution at the gate-tunable suspended graphene-water interface
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TERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis
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Biallelic variants in RBM42 cause a multisystem disorder with neurological, facial, cardiac, and musculoskeletal involvement
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CD300ld on neutrophils is required for tumour-driven immune suppression
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TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease
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Evidence for non-traditional mcr-containing archaea contributing to biological methanogenesis in geothermal springs
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Neoadjuvant adebrelimab in locally advanced resectable esophageal squamous cell carcinoma: a phase 1b trial
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Accelerating the energy transition towards photovoltaic and wind in China
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Prioritizing genes associated with brain disorders by leveraging enhancer-promoter interactions in diverse neural cells and tissues
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Enantiocontrolled macrocyclization by encapsulation of substrates in chiral capsules
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Tipping points detection using reservoir computing
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Designing F/P Hybrid Polymer as Ultrastable Cationic Shielding Interphase for High-Performance Lithium Metal Batteries
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R-loop dependent promoter-proximal termination ensures genome stability
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Emerging Therapies in Cancer Metabolism
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CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma
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Neurodevelopmental risk and adaptation as a model for comorbidity among internalizing and externalizing disorders: genomics and cell-specific expression enriched morphometric study
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Enterotypes of the human gut mycobiome
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Association between vmPFC gray matter volume and smoking initiation in adolescents
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Rare Loss-of-Function variants reveal threshold and multifactorial inheritance of Dextrocardia
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Selective treatment de-intensification by reducing radiation dose and omitting concurrent chemotherapy based on response to induction chemotherapy in HPV-associated oropharyngeal squamous cell carcinoma: the preliminary results of a single-arm, phase
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A putative loop connection between VTA dopamine neurons and nucleus accumbens encodes positive valence to compensate for hunger
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HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury
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Effects of urban living environments on mental health in adults
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Ccdc85c-Par3 condensates couple cell polarity with Notch to control neural progenitor proliferation
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A neural circuit for regulating a behavioral switch in response to prolonged uncontrollability in mice
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Oxytocin Improves Intracerebral Hemorrhage Outcomes by Suppressing Neuronal Pyroptosis and Mitochondrial Fission
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Highly multiplexed bioactivity screening reveals human and microbiota metabolome-GPCRome interactions
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A Pangenome Reference of 36 Chinese populations
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Effect of interval between neoadjuvant chemoradiotherapy and surgery on oncological outcomes in poor responders with locally advanced rectal cancer: a retrospective cohort study
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A CPG-based versatile control framework for metameric earthworm-like robotic locomotion
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CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer
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Imaging of pH distribution inside individual microdroplet by stimulated Raman microscopy
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Molecular Profiling Provides Clinical Insights Into Targeted and Immunotherapies as Well as Colorectal Cancer Prognosis
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Visualizing slow internal relaxations in a two-dimensional glassy system
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Muscle PARP1 inhibition extends lifespan through AMPKα PARylation and activation in Drosophila
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Covalent bonding strategy to enable non-volatile organic cation perovskite for highly stable and efficient solar cells
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A shared neural basis underlying psychiatric comorbidity
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Controlled radical copolymerization of fluoroalkenes by using light-driven redox-relay catalysis
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Signal propagation in complex networks
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Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism
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Early Detection of Molecular Residual Disease and Risk Stratification for Stage I to III Colorectal Cancer via Circulating Tumor DNA Methylation
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INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
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Toward antifragility: Social defeat stress enhances learning and 3 memory in young mice via hippocampal SNAP-25
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Understanding the genetics of human infertility
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A self-charging salt water battery for antitumor therapy
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The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
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The Doping Effect on the Intrinsic Ferroelectricity in Hafnium Oxide-Based Nano-Ferroelectric Devices
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Neuroimaging biomarkers define neurophysiological subtypes with distinct trajectories in schizophrenia
